中西医结合慢性病杂志

目的 利用中医传承计算平台软件，研究刘焯教授在治疗抽动障碍方面的用药经验及组方规律，以传承其临床诊疗经验。方法 收集并整理刘焯教授2022年9月—2023年9月期间治疗抽动障碍的患儿病历，通过中医传承计算平台，录入抽动障碍相关治疗方剂，对处方中药物的频次、四气五味、归经、功效等进行统计，并进行关联规则分析及聚类分析。结果 共收集刘焯教授治疗抽动障碍的处方930则，涉及中药78味，以甘味和苦味为主，其次为辛味、咸味和酸味；四气频次中寒为首，其次为平、温和凉；归经方面以肝经为主，其次为肺经、心经、胃经和脾经等。核心用药包括：钩藤、合欢皮、石菖蒲、茯苓、龙骨、甘草、牡蛎、玄参、珍珠母、白芍和麦冬，排除核心用药后，聚类分析得到4组药物组合。结论 刘焯教授在治疗抽动障碍时，以滋水涵木为主要治则，注重标本同治，以滋阴为本、清热化痰熄风为标，临床效果显著，且在诊疗过程中根据症状进行用药加减。

Objective To study Professor LIU Zhuo's experience and prescription patterns in treating tic disorders using the Traditional Chinese Medicine(TCM) Heritage Computing Platform(Version 3.5), aiming to inherit his clinical diagnostic and therapeutic experience. Methods Collect and organize medical records of children treated by Professor LIU Zhuo for tic disorders from September 2022 to September 2023. Using the TCM Heritage Computing Platform,enter the related treatment prescriptions for tic disorders, conduct statistical analysis on the frequency of herbs used,their properties according to the Five Flavors and Four Natures theory, meridians they target, and their efficacies, as well as perform association rule analysis and cluster analysis. Results A total of 930 prescriptions were collected for the treatment of tic disorders by Professor LIU Zhuo involving 78 different herbs. The primary flavors were Sweet and Bitter, followed by Pungent, Salty, and Sour. In terms of the Four Natures, Cold was predominant, followed by Neutral,Warm, and Cool. The main meridians targeted were the Liver Meridian, followed by the Lung Meridian, Heart Meridian,Stomach Meridian, and Spleen Meridian. Core medications included Uncariae Ramulus cum Uncis(Gouteng), Albiziae Cortex(Hehuanpi), Kaligarmon(Shichangpu), Poria(Fuling), Ostrich Shell(Longgu), Glycyrrhiza(Gancao), Ostrea Concha(Muli), Rehmanniae Radix(Shudihuang), Mother-of-Pearl(Zhenzhumu), White Peony Root(Baishao), and Ophiopogonis Radix(Maidong). After excluding the core prescriptions, cluster analysis yielded four groups of herbal combinations. Conclusion In treating tic disorders, Professor LIU Zhuo primarily follows the principle of nourishing water to enrich wood, emphasizing the simultaneous treatment of root and branch, focusing on nourishing Yin as the root and clearing heat, transforming phlegm, and quelling wind as the branch, achieving significant clinical effects.Adjustments to medication are made based on symptoms during the course of treatment.